paediatrics
paediatrics

Hsa_circ_0006010 and hsa_circ_0002903 in peripheral blood serve as novel diagnostic, surveillance and prognostic biomarkers for disease progression in chronic myeloid leukemia

BMC Cancer. 2024 Sep 20;24(1):1172. doi: 10.1186/s12885-024-12943-x. ABSTRACT BACKGROUND: In the era of tyrosine kinase inhibitor (TKI) treatment, the progression of chronic myeloid leukemia (CML) …

An integrated machine learning model enhances delayed graft function prediction in pediatric renal transplantation from deceased donors

BMC Med. 2024 Sep 20;22(1):407. doi: 10.1186/s12916-024-03624-4. ABSTRACT BACKGROUND: Kidney transplantation is the optimal renal replacement therapy for children with end-stage renal disease; however, delayed …

Development of a signs and symptoms outcome measure for caregivers of patients with methylmalonic acidemia and propionic acidemia (MMAPAQ)

Mol Genet Metab. 2024 Sep 13;143(1-2):108577. doi: 10.1016/j.ymgme.2024.108577. Online ahead of print. ABSTRACT BACKGROUND AND OBJECTIVE: Methylmalonic acidemia (MMA) and propionic acidemia (PA) are rare …

Generation of an infantile GM1 gangliosidosis induced pluripotent stem cell line (CHOCi005-A) for disease modeling and therapeutic testing

Stem Cell Res. 2024 Sep 7;81:103552. doi: 10.1016/j.scr.2024.103552. Online ahead of print. ABSTRACT GM1 gangliosidosis (GM1) is a rare autosomal recessive neurogenerative lysosomal storage disease …

External lumbar drainage for the management of refractory intracranial hypertension in pediatric severe traumatic brain injury: a retrospective single-center case series

J Neurosurg Pediatr. 2024 Sep 20:1-8. doi: 10.3171/2024.7.PEDS24156. Online ahead of print. ABSTRACT OBJECTIVE: Guidelines for the management of pediatric severe traumatic brain injury (TBI) …