paediatrics
paediatrics

Hypoalbuminemia in children with acute lymphoblastic leukemia: relation to asparaginase therapy and impact on high dose methotrexate elimination

Cancer Chemother Pharmacol. 2024 Sep 21. doi: 10.1007/s00280-024-04713-0. Online ahead of print. ABSTRACT PURPOSE: High-dose methotrexate (HDMTX) therapy is an important component in treatment regimens …

Secondary prophylaxis and specialist review compliance in paediatric patients with acute rheumatic fever and rheumatic heart disease in a Western Australian metropolitan setting

J Paediatr Child Health. 2024 Sep 21. doi: 10.1111/jpc.16670. Online ahead of print. ABSTRACT AIM: Rheumatic heart disease (RHD), a consequence of acute rheumatic fever …

Dynamic chromatin architecture identifies new autoimmune-associated enhancers for IL2 and novel genes regulating CD4+ T cell activation

Elife. 2024 Sep 20;13:RP96852. doi: 10.7554/eLife.96852. ABSTRACT Genome-wide association studies (GWAS) have identified hundreds of genetic signals associated with autoimmune disease. The majority of these …