How AI Could Reshape Health Care-Rise in Direct-to-Consumer Models
JAMA. 2025 Feb 24. doi: 10.1001/jama.2025.0946. Online ahead of print. NO ABSTRACT PMID:39992661 | DOI:10.1001/jama.2025.0946
Paediatrics
COVID-19 Vaccination and Odds of Post-COVID-19 Condition Symptoms in Children Aged 5 to 17 Years
JAMA Netw Open. 2025 Feb 3;8(2):e2459672. doi: 10.1001/jamanetworkopen.2024.59672. ABSTRACT IMPORTANCE: An estimated 1% to 3% of children with SARS-CoV-2 infection will develop post-COVID-19 condition (PCC). …
Loss of TRPV4 decreases NFκB-mediated myometrial inflammation and prevents preterm labor
FASEB J. 2025 Feb 28;39(4):e70418. doi: 10.1096/fj.202402949R. ABSTRACT Inflammation is a key initiating event in both spontaneous term and preterm labor. However, the link between …
Subcutaneous Implantable Defibrillators in Young Patients: Arrhythmias, Complications, and Physical Activity
Circ Arrhythm Electrophysiol. 2025 Feb 24:e013365. doi: 10.1161/CIRCEP.124.013365. Online ahead of print. ABSTRACT BACKGROUND: The safety of subcutaneous implantable cardioverter defibrillator (S-ICD) recipients who lead …
Original Study: Association of High-Deductible Health Plans and Complicated Appendicitis among Children
Ann Surg. 2025 Feb 24. doi: 10.1097/SLA.0000000000006680. Online ahead of print. ABSTRACT OBJECTIVE: To determine whether high-deductible health plans (HDHPs) are associated with complicated disease …
Pre-Transplant Immunophenotyping in Pediatric Heart Transplant: A Role for the Immunologist?
Pediatr Transplant. 2025 Mar;29(2):e70052. doi: 10.1111/petr.70052. ABSTRACT BACKGROUND: Pediatric heart transplant recipients are at risk for complications from prolonged exposure to immunosuppressive drugs, possibly worsened …
A Comprehensive Review of Clinically Applied Adeno-Associated Virus-Based Gene Therapies for Ocular Disease
Hum Gene Ther. 2025 Feb 24. doi: 10.1089/hum.2024.252. Online ahead of print. ABSTRACT The eye is an ideal target for gene therapy due its accessibility, …
Balancing Effective Treatments With Potential Threats: The Impact of Biologic Agent Use on Tuberculosis Development in Children With Chronic Inflammatory Disorders
Int J Rheum Dis. 2025 Feb;28(2):e70145. doi: 10.1111/1756-185X.70145. ABSTRACT AIM: We aimed to investigate the frequency and clinical characteristics of tuberculosis in pediatric patients receiving …
Kidney Transplantation in Children and Adolescents With C3 Glomerulopathy or Immune Complex Membranoproliferative Glomerulonephritis: An International Survey of Current Practice
Pediatr Transplant. 2025 Mar;29(2):e70048. doi: 10.1111/petr.70048. ABSTRACT BACKGROUND: Approximately 50% of patients with chronic kidney disease due to C3 glomerulopathy (C3G) or primary immune-complex membranoproliferative …
Temporal trends and unbalanced distribution, in pediatric cutaneous melanoma in 204 countries and territories, 1990-2019
Pediatr Hematol Oncol. 2025 Feb 24:1-11. doi: 10.1080/08880018.2025.2466023. Online ahead of print. ABSTRACT Cutaneous melanoma (CM) is a rare occurrence in the pediatric population and …