Paediatrics
Paediatrics

Authorized or Off-Label Use? A Structured Analysis of Summaries of Product Characteristics with Regard to Authorization in Pediatrics

Pharmaceut Med. 2024 Mar 31. doi: 10.1007/s40290-024-00519-w. Online ahead of print. ABSTRACT PURPOSE: The Summary of Product Characteristics (SmPC) is required to provide unambiguous information …

FNDC5/irisin ameliorates bone loss of type 1 diabetes by suppressing endoplasmic reticulum stress‑mediated ferroptosis

J Orthop Surg Res. 2024 Mar 30;19(1):205. doi: 10.1186/s13018-024-04701-3. ABSTRACT BACKGROUND: Ferroptosis is known to play a crucial role in diabetic osteopathy. However, key genes …

Focused ultrasound-mediated blood-brain barrier opening is safe and feasible with moderately hypofractionated radiotherapy for brainstem diffuse midline glioma

J Transl Med. 2024 Mar 30;22(1):320. doi: 10.1186/s12967-024-05096-9. ABSTRACT BACKGROUND: Diffuse midline glioma (DMG) is a pediatric tumor with dismal prognosis. Systemic strategies have been …