Paediatrics
Paediatrics

A Dutch clinical practice guideline for paediatric palliative care: a systematic review and recommendations on psychosocial care including preloss and bereavement care

BMC Palliat Care. 2025 May 23;24(1):147. doi: 10.1186/s12904-025-01763-w. ABSTRACT BACKGROUND: Children with life-threatening and life-limiting conditions and their families are confronted with many uncertainties, incremental …

Visual Function and Intraocular Pressure Outcomes Following Surgical Intervention in Pediatric Patients with Inflammatory Glaucoma

Ocul Immunol Inflamm. 2025 May 23:1-7. doi: 10.1080/09273948.2025.2508408. Online ahead of print. ABSTRACT PURPOSE: This study evaluates the outcomes of pediatric uveitic glaucoma eyes that …

Disruption of BAG3-mediated BACE1 stabilization alleviates neuropathology and memory deficits in a mouse model of Alzheimer’s disease

Sci Adv. 2025 May 23;11(21):eadt7981. doi: 10.1126/sciadv.adt7981. Epub 2025 May 23. ABSTRACT β-Site amyloid precursor protein (APP)-cleaving enzyme 1 (BACE1) is the rate-limiting enzyme for …

Single-cell profiling demonstrates the combined effect of wheeze phenotype and infant viral infection on airway epithelial development

Sci Adv. 2025 May 23;11(21):eadr9995. doi: 10.1126/sciadv.adr9995. Epub 2025 May 23. ABSTRACT The development of the airway epithelium in asthma is unclear. We characterized nasal …