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Targeting the PS1-ELK1 protein-protein interaction with a peptide-based inhibitor reduces Aβ production and alleviates memory decline in Alzheimer’s disease

Int J Biol Macromol. 2025 Nov 17:149074. doi: 10.1016/j.ijbiomac.2025.149074. Online ahead of print. ABSTRACT Alzheimer’s disease (AD) is a common neurodegenerative disorder among the elderly. …

Influence of Multiple Prior Endoscopic Sinus Surgeries on Dupilumab Efficacy Including Smell Function in the DUPIREAL Population

Clin Otolaryngol. 2025 Nov 19. doi: 10.1111/coa.70060. Online ahead of print. ABSTRACT INTRODUCTION: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a persistent inflammatory condition that …

Mycoplasma pneumoniae in hospitalised children in the post-COVID era: clinical outcomes from a Turkish multicenter cohort

Eur J Pediatr. 2025 Nov 20;184(12):775. doi: 10.1007/s00431-025-06537-3. ABSTRACT Following the COVID-19 pandemic, infections with Mycoplasma pneumoniae (M. pneumoniae) have resurged globally. However, post-pandemic changes …

Risk factors and neurodevelopmental outcomes of post-neonatal seizures up to age three in very-low-birthweight infants based on a nationwide cohort

Sci Rep. 2025 Nov 19;15(1):40905. doi: 10.1038/s41598-025-25206-x. ABSTRACT We assessed the risk factors of post-neonatal anti-epileptic medications after neonatal intensive care unit discharge (PD-AED) and …