Immunogenomic classification reveals prognostic immune signatures in pediatric solid and hematological tumors
Sci Rep. 2026 Mar 31. doi: 10.1038/s41598-026-44997-1. Online ahead of print. NO ABSTRACT PMID:41917096 | DOI:10.1038/s41598-026-44997-1
Loss-of-function variants in ODAD1 disrupt ODA docking and induce actin cytoskeletal remodeling in primary ciliary dyskinesia
Cell Discov. 2026 Mar 31;12(1):25. doi: 10.1038/s41421-026-00875-8. ABSTRACT Primary ciliary dyskinesia (PCD) is a genetically heterogeneous disorder characterized by defective mucociliary clearance due to impaired …
Expert consensus on newborn genetic screening process, interpretation of results, and recall (2026 Edition)
Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2026 Mar 10;43(3):171-179. doi: 10.3760/cma.j.cn511374-20250922-00559. ABSTRACT High-throughput sequencing technology has recently been used in neonatal disease screening. …
Astrocytic APOE3-Christchurch expression ameliorates brain amyloid-β pathology in 5xFAD mice
Transl Psychiatry. 2026 Mar 31;16(1):224. doi: 10.1038/s41398-026-04002-9. ABSTRACT The rare APOE3-Christchurch (APOE3Ch) variant is linked to resistance against PSEN1 p.E280A-driven autosomal dominant Alzheimer’s disease (AD). …
Response to letter regarding “role of the cerebroplacental ratio and non-stress test in predicting adverse perinatal outcomes in high-risk pregnancies
J Matern Fetal Neonatal Med. 2026 Dec;39(1):2650952. doi: 10.1080/14767058.2026.2650952. Epub 2026 Mar 31. NO ABSTRACT PMID:41916877 | DOI:10.1080/14767058.2026.2650952
Long-term neurodevelopmental outcomes and follow-up of germinal matrix-intraventricular hemorrhage in preterm infants
Semin Fetal Neonatal Med. 2026 Mar 25:101733. doi: 10.1016/j.siny.2026.101733. Online ahead of print. ABSTRACT Germinal matrix hemorrhage-intraventricular hemorrhage (GMH-IVH) remains one of the most common …
Mortality in patients with ventricular septal defect in Sweden: a national register study
Open Heart. 2026 Mar 31;13(1):e004098. doi: 10.1136/openhrt-2026-004098. ABSTRACT OBJECTIVES: Ventricular septal defect (VSD) is the most common congenital heart defect. Much remains unclear about the …
Paediatric rheumatologic emergencies: clinical spectrum and outcomes from a 3-year cohort study
Eur J Pediatr. 2026 Mar 31;185(4):230. doi: 10.1007/s00431-026-06829-2. ABSTRACT Paediatric rheumatologic emergencies are rare but potentially fatal, and may present as the first manifestation of …
Shenfu Injection reduces septic lethality by preserving glycocalyx integrity and inhibiting caspase-11-dependent pyroptosis
Inflamm Res. 2026 Apr 1;75(1):76. doi: 10.1007/s00011-026-02224-7. ABSTRACT OBJECTIVE AND DESIGN: Sepsis is a life-threatening condition and a leading cause of in-hospital mortality, characterized by …
A multivariate prediction model to predict delayed CSF sterilization in paediatric post-meningitic hydrocephalus
Childs Nerv Syst. 2026 Apr 1;42(1):144. doi: 10.1007/s00381-026-07235-7. ABSTRACT OBJECTIVE: Post-meningitic hydrocephalus (PMH) in children often needs temporary cerebrospinal fluid (CSF) diversion using an Ommaya …