Pediatr Res. 2025 Jun 4. doi: 10.1038/s41390-025-04163-1. Online ahead of print.
ABSTRACT
In this commentary, we provide additional context to interpret the findings reported on the manuscript by Liu et al., “Neuroprotective effects of vitamin C on hypoxic-ischemic brain injury in neonatal mice” published in this issue of Pediatric Research. IMPACT: Vitamin C is an anti-oxidant with anti-inflammatory effects, which may be neuroprotective against neonatal hypoxic-ischemic (HI) brain injury in a preterm mouse model Several experimental caveats include the timing of intervention, model use and side effects. We provide additional context to the reader in the interpretation of the data.
PMID:40467978 | DOI:10.1038/s41390-025-04163-1
