Utility of Peripheral Blood Testing for Detection and Surveillance of Clonal Hematopoiesis in Predisposed Individuals (CH-IPI)
Paediatrics
Utility of Peripheral Blood Testing for Detection and Surveillance of Clonal Hematopoiesis in Predisposed Individuals (CH-IPI)
Paediatrics

Utility of Peripheral Blood Testing for Detection and Surveillance of Clonal Hematopoiesis in Predisposed Individuals (CH-IPI)

Blood. 2025 Nov 10:blood.2024028042. doi: 10.1182/blood.2024028042. Online ahead of print.

ABSTRACT

We evaluated 108 pediatric patients with bone marrow failure and leukemia predisposition for presence of clonal hematopoiesis in peripheral blood (PB) and bone marrow (BM). We found robust PB-BM concordance for mutations but decreased sensitivity in PB for chromosomal abnormalities.

PMID:41335385 | DOI:10.1182/blood.2024028042