Understanding post-operative refractive outcome in pediatrics after IOL implementation: factors and predictors
Understanding post-operative refractive outcome in pediatrics after IOL implementation: factors and predictors

Understanding post-operative refractive outcome in pediatrics after IOL implementation: factors and predictors

Int Ophthalmol. 2024 Sep 4;44(1):364. doi: 10.1007/s10792-024-03280-w.

ABSTRACT

BACKGROUND: In pediatric ophthalmology, calculating intra-ocular lens (IOL) power can be challenging. It is important to predict if the post-surgery refractive error (RE) will meet the intended refractive goal. In this study, we aimed to investigate the factors and predictors influencing RE outcomes in children undergoing IOL implantation.

METHODS: This was a retrospective cross-sectional cohort study that involved 47 eyes with congenital cataracts underwent IOL implantation. Each patient underwent follow-up visits at two months and two years’ post-surgery. The IOL power calculations were conducted using the Holladay 1 formula, and both the prediction error (PE) and absolute prediction error (APE) were calculated.

RESULTS: The mean age was 6.52 ± 4.61 years, with an age range of 1-15 years. The mean IOL power was 20.31 ± 6.57 D, and the mean post-operative refraction was 1.31 ± 2.65 D. The mean of PE and APE were 0.67 ± 1.77 and 1.55 ± 1.06 D, respectively. Whereas PE was correlated to axial length with an R-value of – 0.29 (P = 0.04). The calculation method had a significant negative relationship with APE and PE, with coefficients of – 1.05 (P = 0.009) and – 1.81 (P = 0.009), respectively.

CONCLUSION: High astigmatism was associated with greater errors in the refractive outcome. The calculation methods had the most considerable impact on the post-operative RE. The customization of surgical approaches to accommodate individual characteristics is crucial. Further research with diverse subgroups is needed to comprehensively understand the influence of each factor.

PMID:39230787 | DOI:10.1007/s10792-024-03280-w