Thoracic Hybrid Lesion: A Rare Case of Two Congenital Malformations
Thoracic Hybrid Lesion: A Rare Case of Two Congenital Malformations

Thoracic Hybrid Lesion: A Rare Case of Two Congenital Malformations

Cureus. 2024 Dec 19;16(12):e76023. doi: 10.7759/cureus.76023. eCollection 2024 Dec.

ABSTRACT

Cystic cuboid adenomatous malformations (CCAM) are congenital pulmonary lesions, usually benign, that can progress into malignancy. Bronchopulmonary sequestration (BPS) is another type of malformation that consistsof an ectopic pulmonary tissue mass that doesn’t participate in blood-gas exchanges, with vascularization provided by anomalous branches of the thoracic aorta. Hybrid lesions are lesions that have histological features of CCAM but with systemic vascularization, a pathognomonic sign of BPS. These lesions are rare and difficult to diagnose. The diagnoses are mostly made in the pre-or neonatal phases of life. The diagnosis in adults is uncommon. The treatment is surgical resection of the lesion or wedge lobectomy. The case report describes a case of a hybrid lesion diagnosed in an asymptomatic adult, as well as a review of the adequate diagnostic workup for pulmonary lesions. In the literature, there are few cases of congenital lung lesions described in adults.

PMID:39834982 | PMC:PMC11743575 | DOI:10.7759/cureus.76023