Arch Pediatr. 2025 Nov 5:S0929-693X(25)00210-6. doi: 10.1016/j.arcped.2025.09.006. Online ahead of print.
ABSTRACT
BACKGROUND: The increase in allergic, autoimmune, and metabolic diseases observed in recent decades correlates with increased exposure to new chemicals that can damage the epithelial barrier, regardless of its location, the skin, respiratory, and digestive tract. Infants are often exposed to detergents and disinfectants from birth.
OBJECTIVES, METHODS, AND SETTING: Published data indicate a potentially harmful impact of these chemicals on the epithelial barrier, which could promote allergies. The aim of this article is to review the available data on how these chemicals affect the epithelial barrier.
RESULTS: We depict the likely harmful role of common household products in the development of allergies in children.
CONCLUSION: We suggest simple changes in everyday life aimed at reducing contact with these products in infants and young children.
PMID:41198450 | DOI:10.1016/j.arcped.2025.09.006
