Technical recommendations for analyzing oxylipins by liquid chromatography-mass spectrometry
Technical recommendations for analyzing oxylipins by liquid chromatography-mass spectrometry

Technical recommendations for analyzing oxylipins by liquid chromatography-mass spectrometry

Sci Signal. 2025 May 20;18(887):eadw1245. doi: 10.1126/scisignal.adw1245. Epub 2025 May 20.

ABSTRACT

Several oxylipins are potent lipid mediators that regulate diverse aspects of health and disease and whose quantitative analysis by liquid chromatography-mass spectrometry (LC-MS) presents substantial technical challenges. As members of the lipidomics community, we developed technical recommendations to ensure best practices when quantifying oxylipins by LC-MS.

PMID:40392938 | DOI:10.1126/scisignal.adw1245