paediatrics
paediatrics

Long-term outcomes of laparoscopic-assisted versus complete transanal endorectal pull-through technique for classic segment Hirschsprung’s disease

Pediatr Surg Int. 2024 Dec 13;41(1):26. doi: 10.1007/s00383-024-05924-5. ABSTRACT BACKGROUND: The efficacy of transanal endorectal pull-through (TERPT) in treating classic Hirschsprung’s disease may be enhanced …

Copper chelation redirects neutrophil function to enhance anti-GD2 antibody therapy in neuroblastoma

Nat Commun. 2024 Dec 12;15(1):10462. doi: 10.1038/s41467-024-54689-x. ABSTRACT Anti-disialoganglioside (GD2) antibody therapy has provided clinical benefit to patients with neuroblastoma however efficacy is likely impaired …

Clearing MRD positivity with blinatumomab in pediatric B-cell acute lymphoblastic leukemia: insights from droplet digital PCR and flow cytometry

Ann Hematol. 2024 Dec 13. doi: 10.1007/s00277-024-06126-8. Online ahead of print. ABSTRACT Blinatumomab has shown to improve survival outcomes in B-cell acute lymphoblastic leukemia (B-ALL) …

Bi-allelic MYMX variants cause a syndromic congenital myopathy with recognizable facial palsy, growth restriction, and dysmorphism

Eur J Hum Genet. 2024 Dec 12. doi: 10.1038/s41431-024-01759-9. Online ahead of print. ABSTRACT Myogenic fusion, primarily regulated by the Myomaker and Myomixer proteins, is …