paediatrics
paediatrics

Automated reporting of primaquine dose efficacy, tolerability and safety for Plasmodium vivax malaria using a systematic review and individual patient data meta-analysis

Malar J. 2025 Nov 14;24(1):400. doi: 10.1186/s12936-025-05642-w. ABSTRACT BACKGROUND: The antirelapse efficacy of primaquine is related to the total dose administered, whereas the risks of …

Exploring barriers and facilitators of preceptorship in undergraduate health professions education: insights from a qualitative needs assessment among preceptors in Eastern Uganda

BMC Med Educ. 2025 Nov 14;25(1):1605. doi: 10.1186/s12909-025-08160-0. ABSTRACT BACKGROUND: Clinical preceptorship plays a critical role in bridging theoretical knowledge and practical skills for health …

Comparative effectiveness of metformin and alogliptin combination therapy versus metformin monotherapy in patients with type 2 diabetes: an emulated target trial

BMC Endocr Disord. 2025 Nov 14;25(1):264. doi: 10.1186/s12902-025-02087-9. ABSTRACT BACKGROUND: As type 2 diabetes mellitus (T2DM) has emerged as a global health challenge, various treatment …

Topical vancomycin for surgical site infection prophylaxis in craniotomies and noninstrumented spinal procedures: a randomized controlled trial

J Neurosurg. 2025 Nov 14:1-10. doi: 10.3171/2025.6.JNS23694. Online ahead of print. ABSTRACT OBJECTIVE: The objective of this study was to determine the efficacy of topical …

Predictors of seizure outcomes and postoperative cognitive changes after total corpus callosotomy in school-aged children, adolescents, and adults

J Neurosurg Pediatr. 2025 Nov 14:1-10. doi: 10.3171/2025.7.PEDS25232. Online ahead of print. ABSTRACT OBJECTIVE: Although total corpus callosotomy (TCC) is attempted for better seizure control …

Socioeconomic and geographic factors associated with the timing of surgical intervention for sagittal craniosynostosis in Georgia

J Neurosurg Pediatr. 2025 Nov 14:1-8. doi: 10.3171/2025.7.PEDS2548. Online ahead of print. ABSTRACT OBJECTIVE: Nonsyndromic sagittal craniosynostosis is the most common form of craniosynostosis, and …

Guided Inhalation via Electronic Monitoring in Children With Uncontrolled Asthma (the IMAGINE Study): Randomized Controlled Trial

JMIR Pediatr Parent. 2025 Nov 14;8:e78526. doi: 10.2196/78526. ABSTRACT BACKGROUND: Pediatric asthma is the most common chronic illness among children in the Netherlands. Scheduled hospital …

Methods for Addressing Missingness in Electronic Health Record Data for Clinical Prediction Models: Comparative Evaluation

JMIR Med Inform. 2025 Nov 14;13:e79307. doi: 10.2196/79307. ABSTRACT BACKGROUND: Missing data are a common challenge in electronic health record (EHR)-based prediction modeling. Traditional imputation …