paediatrics
paediatrics

paediatrics

Paediatrics

Newborns with ARDS originating from sepsis of extrapulmonary origin exhibit worse prognoses: findings from a multicenter study in China

Eur J Pediatr. 2025 Dec 4;184(12):819. doi: 10.1007/s00431-025-06584-w. ABSTRACT Research on the infection-related etiologies of neonatal acute respiratory distress syndrome (NARDS) remains limited. This study …

Paediatrics

A de Novo 2q23.1-2q23.3 duplication in a neonate with anemia, thrombocytopenia, and hypospadias: clinical and genomic characterization

Mol Cytogenet. 2025 Dec 4. doi: 10.1186/s13039-025-00741-4. Online ahead of print. ABSTRACT BACKGROUND: Copy number variations (CNVs) of uncertain significance (VUS) are increasingly identified through …

Paediatrics

The clinical and cost effectiveness of a conservative treatment pathway compared to appendicectomy in children with uncomplicated acute appendicitis: study protocol for a randomised controlled multi-centre open-label parallel-group non-inferiority trial (CONTRACT 2 trial) in the United Kingdom (UK)

Trials. 2025 Dec 4. doi: 10.1186/s13063-025-09282-y. Online ahead of print. ABSTRACT BACKGROUND: Currently, the most frequently used treatment for acute appendicitis in children in the …

Paediatrics

Overview of pediatric and adult lysosomal acid lipase deficiency: expert recommendations from a Gulf cooperation council working group

Orphanet J Rare Dis. 2025 Dec 5. doi: 10.1186/s13023-025-04158-5. Online ahead of print. ABSTRACT BACKGROUND: Lysosomal acid lipase deficiency (LAL-D) is an autosomal recessive ultrarare …

Paediatrics

Comparative effectiveness of advanced radiotherapy techniques for brain cancers: A systematic review with an emphasis on dosimetric variability

Phys Med. 2025 Dec 3;140:105682. doi: 10.1016/j.ejmp.2025.105682. Online ahead of print. ABSTRACT BACKGROUND: Central nervous system (CNS) cancers pose a significant burden on global health. …