paediatrics
paediatrics

Vedolizumab Versus Other Biologics and the Risk of Venous Thromboembolism in Patients with Pediatric-Onset Inflammatory Bowel Diseases: A Target Trial Emulation Study

Paediatr Drugs. 2025 Oct 8. doi: 10.1007/s40272-025-00717-2. Online ahead of print. ABSTRACT BACKGROUND: Pediatric-onset inflammatory bowel diseases (IBD) are associated with an elevated risk of …

The PHOX2B c.428A>G missense variant affects post-transcriptional regulation and may explain the absence of neural crest-derived tumors in congenital central hypoventilation syndrome

Front Physiol. 2025 Sep 22;16:1616994. doi: 10.3389/fphys.2025.1616994. eCollection 2025. ABSTRACT INTRODUCTION: Heterozygous mutations in the paired-like homeobox 2b (PHOX2B) gene cause congenital central hypoventilation syndrome …

Associations between objectively and subjectively measured sleep outcomes among elementary school children in Rhode Island

Front Pediatr. 2025 Sep 22;13:1622943. doi: 10.3389/fped.2025.1622943. eCollection 2025. ABSTRACT OBJECTIVE: Although sleep is essential for healthy child development, parents generally misconstrue definitions of sleep …

Prevalence and duration of clinical symptoms of pediatric long COVID: findings from a one-year prospective study

Front Pediatr. 2025 Sep 22;13:1645228. doi: 10.3389/fped.2025.1645228. eCollection 2025. ABSTRACT BACKGROUND: Long COVID in children remains a poorly understood condition with wide variability in clinical …