paediatrics
paediatrics

Delayed diagnosis and clinical course of alpha-mannosidosis: A retrospective study of 25 patients with varying severity

Genet Med Open. 2025 Oct 13;3:103465. doi: 10.1016/j.gimo.2025.103465. eCollection 2025. ABSTRACT PURPOSE: Alpha-mannosidosis is an ultrarare lysosomal storage disorder characterized by considerable diagnostic delays due …

Revealing the genotype-phenotype correlations of congenital hypothyroidism in Yunnan Province, Southwest China

Front Endocrinol (Lausanne). 2025 Nov 17;16:1640108. doi: 10.3389/fendo.2025.1640108. eCollection 2025. ABSTRACT CONTEXT: Congenital hypothyroidism (CH) is a congenital endocrine disorder with diverse clinical presentations. The …

Small patients – Big needs: A material-based approach to develop miniaturised valves for congenital heart diseases

Bioact Mater. 2025 Nov 17;57:430-444. doi: 10.1016/j.bioactmat.2025.11.011. eCollection 2026 Mar. ABSTRACT Paediatric valve replacements cannot be built by simply scaling down bigger-sized valve implants. Innovative …

Clinical characteristics and mortality risk factors among hospitalized infants and children with pertussis in China: a retrospective study

Front Public Health. 2025 Nov 17;13:1663885. doi: 10.3389/fpubh.2025.1663885. eCollection 2025. ABSTRACT BACKGROUND: The resurgence of pertussis has emerged as a significant global public health threat. …

The Veggie Vouchers intervention to promote SNAP fruit and vegetable incentive program use for families with food insecurity: a single arm feasibility study

Pilot Feasibility Stud. 2025 Dec 2. doi: 10.1186/s40814-025-01732-3. Online ahead of print. ABSTRACT BACKGROUND: The Supplemental Nutrition Assistance Program (SNAP) has financial incentive programs where …

Five-year surveillance of antimicrobial resistance patterns among blood culture isolates at the University Teaching Hospital, Kigali, Rwanda

Ann Clin Microbiol Antimicrob. 2025 Dec 2. doi: 10.1186/s12941-025-00837-0. Online ahead of print. ABSTRACT BACKGROUND: Bloodstream infections remain a major cause of morbidity and mortality …