paediatrics
paediatrics

Global regulatory variability in small-molecule inhibitor approvals: Differences in timelines, dosing, and pediatric indications across FDA, EMA, and PMDA

Clin Transl Oncol. 2025 Oct 4. doi: 10.1007/s12094-025-04066-x. Online ahead of print. ABSTRACT PURPOSE: Small-molecule inhibitors have transformed oncology in recent years. This study compared …

Epstein-Barr virus infection and vitamin D deficiency are both “causal” for multiple sclerosis (MS) – could the common denominator be their effects on hepcidin levels?

Metab Brain Dis. 2025 Oct 4;40(7):279. doi: 10.1007/s11011-025-01678-8. ABSTRACT Multiple sclerosis (MS) is a neurological disorder characterized by damage to the myelin sheaths surrounding axons …

Molecular-based evidence for school transmission of enteroaggregative Escherichia coli among apparently healthy children attending nursery, infant, and primary schools in Madrid (Spain)

Eur J Pediatr. 2025 Oct 4;184(11):658. doi: 10.1007/s00431-025-06430-z. ABSTRACT Information on the epidemiology, transmission dynamics, and public health impact of enteroaggregative Escherichia coli (EAEC) infection …