paediatrics
paediatrics

Multiple phenotypic traits including developmental impairment in a Chinese family with infantile convulsion and choreoathetosis syndrome: a case study expanding the clinical spectrum of prrt2-related syndrome

BMC Pediatr. 2025 Oct 6;25(1):769. doi: 10.1186/s12887-025-06180-9. ABSTRACT BACKGROUND: Pathogenic heterozygous variants in the gene encoding proline-rich transmembrane protein 2 (PRRT2) have been recently identified …

The relationship between stress, anxiety, and health literacy in parents of children with chronic gastroenterological diseases: a multi-center cross-sectional study

BMC Public Health. 2025 Oct 6;25(1):3357. doi: 10.1186/s12889-025-24329-0. ABSTRACT BACKGROUND: Parents caring for a child with a chronic illness experience a significant psychological burden, which …

Collagen-disrupting attIL12 TIL therapy boosts deep T cell infiltration via dual signaling activation and CCKAR reduction in sarcomas

Proc Natl Acad Sci U S A. 2025 Oct 14;122(41):e2507542122. doi: 10.1073/pnas.2507542122. Epub 2025 Oct 6. ABSTRACT Tumor-targeted T cell therapies of various types have …