paediatrics
paediatrics

Triggered Electromyography for Assessment of Pedicle Screw Placement in Pediatric Spinal Deformity Surgery: Is It Useful?

Spine (Phila Pa 1976). 2025 Oct 7. doi: 10.1097/BRS.0000000000005526. Online ahead of print. ABSTRACT STUDY DESIGN: Retrospective cohort study. OBJECTIVE: To evaluate the characteristics and …

An ectopic Hedgehog signaling axis drives directional tumor outgrowth in a mouse model of hereditary multiple osteochondromas

Sci Signal. 2025 Oct 7;18(907):eadu6357. doi: 10.1126/scisignal.adu6357. Epub 2025 Oct 7. ABSTRACT Osteochondromas characterize the rare pediatric disorder hereditary multiple osteochondromas (HMO). The tumors originate …

Retatrutide Improves Steatohepatitis in an Accelerated Mouse Model of Diet-Induced Steatohepatitis with a Fructose Binge

Am J Physiol Gastrointest Liver Physiol. 2025 Oct 7. doi: 10.1152/ajpgi.00164.2025. Online ahead of print. ABSTRACT Fructose consumption contributes to metabolic dysfunction-associated steatohepatitis (MASH). Retatrutide …

Implications for cystic fibrosis therapy: Potentiator icenticaftor is superior to ivacaftor in improving function and maintaining stability of F508del CFTR

Sci Prog. 2025 Oct-Dec;108(4):368504251384892. doi: 10.1177/00368504251384892. Epub 2025 Oct 7. ABSTRACT ObjectiveThe objective of this study was to compare CFTR potentiators icenticaftor versus ivacaftor (IVA) …