paediatrics
paediatrics

A novel BAG5 variant impairs the ER stress response pathway, causing dilated cardiomyopathy and arrhythmia

Sci Rep. 2024 May 25;14(1):11980. doi: 10.1038/s41598-024-62764-y. ABSTRACT Pathogenic BAG5 variants recently linked to dilated cardiomyopathy (DCM) prompt further investigation into phenotypic, mutational, and pathomechanistic …

Comparison of current to past outcomes in congenital diaphragmatic hernia using mri observed-to-expected total fetal lung volume

J Perinatol. 2024 May 25. doi: 10.1038/s41372-024-02008-z. Online ahead of print. ABSTRACT BACKGROUND: Fetal Centers use imaging studies to predict congenital diaphragmatic hernia (CDH) prognosis …

Differences in treatment trajectory following brief paediatric inpatient admissions for children and young people with eating disorders

Eur Eat Disord Rev. 2024 May 25. doi: 10.1002/erv.3105. Online ahead of print. ABSTRACT OBJECTIVE: Little is known about factors associated with treatment trajectory following …

Chaperone-mediated autophagy protects the bone formation from excessive inflammation through PI3K/AKT/GSK3β/β-catenin pathway

FASEB J. 2024 May 31;38(10):e23646. doi: 10.1096/fj.202302425R. ABSTRACT Multiple regulatory mechanisms are in place to ensure the normal processes of bone metabolism, encompassing both bone …

Upregulation of KDM6B in the anterior cingulate cortex contributes to neonatal maternal deprivation-induced chronic visceral pain in mice

Mol Pain. 2024 May 25:17448069241260349. doi: 10.1177/17448069241260349. Online ahead of print. ABSTRACT Irritable bowel syndrome (IBS) is a prevalent functional gastrointestinal disease characterized by chronic …

Construction and validation of nomogram prognostic model for predicting survival in hepatoblastoma patients: a population-based study

Updates Surg. 2024 May 25. doi: 10.1007/s13304-024-01814-6. Online ahead of print. ABSTRACT For patients with hepatoblastoma (HB), current staging system is not accurate in predicting …