Patient-derived organoid biobank identifies epigenetic dysregulation of intestinal epithelial MHC-I as a novel mechanism in severe Crohn’s Disease
Gut. 2024 Jun 10:gutjnl-2024-332043. doi: 10.1136/gutjnl-2024-332043. Online ahead of print. ABSTRACT OBJECTIVE: Epigenetic mechanisms, including DNA methylation (DNAm), have been proposed to play a key …