paediatrics
paediatrics

Patient-derived organoid biobank identifies epigenetic dysregulation of intestinal epithelial MHC-I as a novel mechanism in severe Crohn’s Disease

Gut. 2024 Jun 10:gutjnl-2024-332043. doi: 10.1136/gutjnl-2024-332043. Online ahead of print. ABSTRACT OBJECTIVE: Epigenetic mechanisms, including DNA methylation (DNAm), have been proposed to play a key …

Effectiveness of nirsevimab immunoprophylaxis against respiratory syncytial virus-related outcomes in hospital and primary care settings: a retrospective cohort study in infants in Catalonia (Spain)

Arch Dis Child. 2024 Jun 10:archdischild-2024-327153. doi: 10.1136/archdischild-2024-327153. Online ahead of print. ABSTRACT BACKGROUND: In Catalonia, infants under 6 months old were eligible to receive …

Association of childhood food consumption and dietary pattern with cardiometabolic risk factors and metabolomics in late adolescence: prospective evidence from ‘Children of 1997’ birth cohort

J Epidemiol Community Health. 2024 Jun 10:jech-2023-221245. doi: 10.1136/jech-2023-221245. Online ahead of print. ABSTRACT BACKGROUND: Healthy diet might protect against cardiometabolic diseases, but uncertainty exists …

Clinical spectrum, phenotypic and molecular characterization, and antifungal susceptibility of an emerging human pathogen, Acrophialophora, from India

Med Mycol. 2024 Jun 10:myae061. doi: 10.1093/mmy/myae061. Online ahead of print. ABSTRACT Acrophialophora is implicated in superficial and invasive infections, especially in immunosuppressed individuals. The …

Sugammadex use in pediatric patients with stage IV-V chronic kidney disease in a quaternary referral hospital: a case series

BMC Anesthesiol. 2024 Jun 10;24(1):206. doi: 10.1186/s12871-024-02584-9. ABSTRACT BACKGROUND: Sugammadex is a pharmacologic agent that provides rapid reversal of neuromuscular blockade via encapsulation of the …

First incidence of extrarenal wilms tumor within the spinal canal in the adult population: a novel case report and literature review

BMC Urol. 2024 Jun 10;24(1):119. doi: 10.1186/s12894-024-01508-6. ABSTRACT BACKGROUND: Wilms tumor (WT), also known as nephroblastoma, is rare in adults, accounting for merely 3% of …