paediatrics
paediatrics

High Healthcare Costs in Childhood Inflammatory Bowel Disease: Development of a Prediction Model Using Linked Clinical and Health Administrative Data

Inflamm Bowel Dis. 2024 Jul 19:izae148. doi: 10.1093/ibd/izae148. Online ahead of print. ABSTRACT BACKGROUND: The incidence of pediatric-onset inflammatory bowel disease (IBD) and the costs …

Importance of duodenal stump reinforcement to prevent stump leakage after gastrectomy: a large-scale multicenter retrospective study (KSCC DELICATE study)

Gastric Cancer. 2024 Jul 19. doi: 10.1007/s10120-024-01538-x. Online ahead of print. ABSTRACT BACKGROUND: The significance of reinforcement of the duodenal stump with seromuscular sutures and …

Association of PLCE1 (rs7922612) and COL4A3 (rs375290088) Genetic Variants with the Risk of Nephrotic Syndrome in Egyptian Pediatric Patients

Biochem Genet. 2024 Jul 19. doi: 10.1007/s10528-024-10883-6. Online ahead of print. ABSTRACT Nephrotic syndrome is one of the most prevalent pediatric kidney illnesses seen in …

Alzheimer’s disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling

Elife. 2024 Jul 19;12:RP90690. doi: 10.7554/eLife.90690. ABSTRACT Amyloid β (Aβ) peptides accumulating in the brain are proposed to trigger Alzheimer’s disease (AD). However, molecular cascades …