paediatrics
paediatrics

Proton pump inhibitor effect on esophageal protein signature of eosinophilic esophagitis, prediction, and evaluation of treatment response

Allergy. 2024 Aug 2. doi: 10.1111/all.16261. Online ahead of print. ABSTRACT BACKGROUND: Recently, we have identified a dysregulated protein signature in the esophageal epithelium of …

Candesartan restores blood-brain barrier dysfunction, mitigates aberrant gene expression, and extends lifespan in a knockin mouse model of epileptogenesis

Clin Sci (Lond). 2024 Aug 2:CS20240771. doi: 10.1042/CS20240771. Online ahead of print. ABSTRACT Blockade of Angiotensin type 1 receptor (AT1R) has potential therapeutic utility in …

Impact of cancer on the mortality of patients with idiopathic inflammatory myopathies by flexible parametric multistate modelling

J Intern Med. 2024 Aug 2. doi: 10.1111/joim.20003. Online ahead of print. ABSTRACT BACKGROUND: Patients with idiopathic inflammatory myopathies (IIM) have an increased risk of …

Real-world data confirm elexacftor/tezacaftor/ivacaftor modulators halves sweat chloride concentration in eligible people with cystic fibrosis

APMIS. 2024 Aug 2. doi: 10.1111/apm.13453. Online ahead of print. ABSTRACT Sweat chloride concentration, a diagnostic feature in cystic fibrosis (CF), reflects CF transmembrane conductance …

Correlation of Zinc and Copper Levels In Mothers and Cord Blood of Neonates With Prematurity and Intrauterine Growth Pattern

Cureus. 2024 Jul 2;16(7):e63674. doi: 10.7759/cureus.63674. eCollection 2024 Jul. ABSTRACT Background Trace elements like zinc and copper are indispensable for human growth and development, exerting …

Multi-locus imprinting disturbance (MLID): interim joint statement for clinical and molecular diagnosis

Clin Epigenetics. 2024 Aug 1;16(1):99. doi: 10.1186/s13148-024-01713-y. ABSTRACT BACKGROUND: Imprinting disorders are rare diseases resulting from altered expression of imprinted genes, which exhibit parent-of-origin-specific expression …