paediatrics
paediatrics

paediatrics

Paediatrics

A Novel Case of IFNAR1 Deficiency Identified a Common Canonical Splice Site Variant in DOCK8 in Western Polynesia: The Importance of Validating Variants of Unknown Significance in Under-Represented Ancestries

J Clin Immunol. 2024 Aug 5;44(8):170. doi: 10.1007/s10875-024-01774-x. ABSTRACT Advanced genomic technologies such as whole exome or whole genome sequencing have improved diagnoses and disease …

Paediatrics

Time to recovery from severe community-acquired pneumonia and its predictors among 6 to 59 months of age children admitted to South Wollo zone public hospitals, North East Ethiopia: a prospective follow-up study

Pneumonia (Nathan). 2024 Aug 5;16(1):14. doi: 10.1186/s41479-024-00135-x. ABSTRACT INTRODUCTION: Ethiopia is one of those countries with higher burden of community acquired pneumonia among its people, …

Paediatrics

Insights into Patient Experiences with Facilitated Subcutaneous Immunoglobulin Therapy in Primary Immune Deficiency: A Prospective Observational Cohort

J Clin Immunol. 2024 Aug 5;44(8):169. doi: 10.1007/s10875-024-01771-0. ABSTRACT BACKGROUND: Immunoglobulin G replacement therapy (IgRT), intravenous (IV) and subcutaneous (SC) routes, is pivotal in treatment …

Paediatrics

Single nucleotide polymorphism rs7961894, platelet morphological parameters and lipid profile in children with type 1 diabetes: a potential relationship

Eur J Pediatr. 2024 Aug 5. doi: 10.1007/s00431-024-05694-1. Online ahead of print. ABSTRACT Increased cardiovascular risk has been associated with certain platelet morphological parameters, and …

Paediatrics

Risk factors, incidence, and outcomes of neonatal respiratory extracorporeal membrane oxygenation including association with therapeutic hypothermia in California during 2013-2020

J Perinatol. 2024 Aug 4. doi: 10.1038/s41372-024-02067-2. Online ahead of print. ABSTRACT OBJECTIVE: To evaluate the incidence, indications and outcomes with neonatal extracorporeal membrane oxygenation …

Paediatrics

Public drinking water contaminant estimates for birth cohorts in the Environmental Influences on Child Health Outcomes (ECHO) Cohort

J Expo Sci Environ Epidemiol. 2024 Aug 4. doi: 10.1038/s41370-024-00699-2. Online ahead of print. ABSTRACT BACKGROUND: The United States Environmental Protection Agency (USEPA) regulates over …

Paediatrics

Astragaloside IV promotes the pyroptosis of airway smooth muscle cells in childhood asthma by suppressing HMGB1/RAGE axis to inactivate NF-κb pathway

Autoimmunity. 2024 Dec;57(1):2387100. doi: 10.1080/08916934.2024.2387100. Epub 2024 Aug 4. ABSTRACT Childhood asthma, a common chronic childhood disease, leads to high mortality and morbidity in the …