paediatrics
paediatrics

Transcriptional and epigenetic characterization of a new in vitro platform to model the formation of human pharyngeal endoderm

Genome Biol. 2024 Aug 8;25(1):211. doi: 10.1186/s13059-024-03354-z. ABSTRACT BACKGROUND: The Pharyngeal Endoderm (PE) is an extremely relevant developmental tissue, serving as the progenitor for the …

Pediatric therapy-related hematologic neoplasms show enrichment for KMT2A rearrangement and lymphoblastic phenotype

Leuk Lymphoma. 2024 Aug 8:1-13. doi: 10.1080/10428194.2024.2376166. Online ahead of print. ABSTRACT In children, therapy-related hematologic neoplasms (t-HN) are uncommon. Many are driven by genetic …