paediatrics
paediatrics

Exploring Biliverdin’s Molecular Interactions with Cu- and Fe-Based MOFs: A Unified In Vitro Study with Photoacoustic Analysis

Langmuir. 2024 Aug 21. doi: 10.1021/acs.langmuir.3c03584. Online ahead of print. ABSTRACT Metal-organic frameworks (MOFs) have shown promise in enhancing the stability of biomolecules. Herein, biliverdin …

A20 haploinsufficiency disturbs immune homeostasis and drives the transformation of lymphocytes with permissive antigen receptors

Sci Adv. 2024 Aug 23;10(34):eadl3975. doi: 10.1126/sciadv.adl3975. Epub 2024 Aug 21. ABSTRACT Genetic TNFAIP3 (A20) inactivation is a classical somatic lymphoma lesion and the genomic …

Evolving Concepts in Pathophysiology, Screening, and Prevention of Type 1 Diabetes: Report of Diabetes Mellitus Interagency Coordinating Committee Workshop

Diabetes. 2024 Aug 21:dbi240020. doi: 10.2337/dbi24-0020. Online ahead of print. ABSTRACT The approval of teplizumab to delay the onset of type 1 diabetes is an …

Assessing Psychosocial Risk and Resilience to Support Readiness for Gene Therapy in Sickle Cell Disease: A Consensus Statement

JAMA Netw Open. 2024 Aug 1;7(8):e2429443. doi: 10.1001/jamanetworkopen.2024.29443. ABSTRACT IMPORTANCE: The introduction of gene therapies into the clinical care landscape for individuals living with sickle …

Allogeneic Hematopoietic Stem Cell Transplantation in Immunodeficiency-Centromeric Instability-Facial Dysmorphism (ICF) Syndrome: an EBMT/ESID Inborn Errors Working Party Study

J Clin Immunol. 2024 Aug 21;44(8):182. doi: 10.1007/s10875-024-01786-7. ABSTRACT Immunodeficiency-Centromeric instability-Facial dysmorphism (ICF) syndrome is an inborn error of immunity characterized by progressive immune dysfunction …