paediatrics
paediatrics

Success Rate and Predicting Factors for Repeated High-Dose Intradetrusor Dysport Injections in Children With Neurogenic Bladder: A Retrospective Study

Neurourol Urodyn. 2024 Sep 10. doi: 10.1002/nau.25580. Online ahead of print. ABSTRACT OBJECTIVES: Evaluating the effectiveness and safety of repeated high-dose intradetrusor abobotulinumtoxin A (Dysport®) …

Helicobacter pylori seropositivity associates with hyperglycemia, but not obesity, in Danish children and adolescents

BMC Med. 2024 Sep 11;22(1):379. doi: 10.1186/s12916-024-03591-w. ABSTRACT BACKGROUND: Helicobacter pylori colonizes the human stomach and may affect the inflammatory response, hormone production related to …

AI-derived comparative assessment of the performance of pathogenicity prediction tools on missense variants of breast cancer genes

Hum Genomics. 2024 Sep 11;18(1):99. doi: 10.1186/s40246-024-00667-9. ABSTRACT Single nucleotide variants (SNVs) can exert substantial and extremely variable impacts on various cellular functions, making accurate …

How are maternal and fetal outcomes incorporated when measuring benefits of interventions in pregnancy? Findings from a systematic review of cost-utility analyses

Health Qual Life Outcomes. 2024 Sep 11;22(1):75. doi: 10.1186/s12955-024-02293-4. ABSTRACT OBJECTIVE: Medical interventions used in pregnancy can affect the length and quality of life of …

Development and validation of machine-learning models of diet management for hyperphenylalaninemia: a multicenter retrospective study

BMC Med. 2024 Sep 11;22(1):377. doi: 10.1186/s12916-024-03602-w. ABSTRACT BACKGROUND: Assessing dietary phenylalanine (Phe) tolerance is crucial for managing hyperphenylalaninemia (HPA) in children. However, traditionally, adjusting …

The effect of family structure on the still-missing heritability and genomic prediction accuracy of type 2 diabetes

Hum Genomics. 2024 Sep 11;18(1):98. doi: 10.1186/s40246-024-00669-7. ABSTRACT This study aims to assess the effect of familial structures on the still-missing heritability estimate and prediction …

Association between real-time polymerase chain reaction cycle threshold value and clinical presentation in children with Bordetella pertussis

Ital J Pediatr. 2024 Sep 11;50(1):173. doi: 10.1186/s13052-024-01753-3. ABSTRACT BACKGROUND: The cycle threshold (Ct) value is inversely proportional to the number of copies of the …