paediatrics
paediatrics

Development of the Better Research Interactions for Every Family (BRIEF) intervention to support recruitment for neonatal clinical trials: an intervention mapping guided approach

Trials. 2024 Sep 12;25(1):610. doi: 10.1186/s13063-024-08446-6. ABSTRACT BACKGROUND: Recruitment for neonatal clinical trials can be particularly challenging. Low enrollment rates bias the research population and …

Comparison of targeted next-generation sequencing and metagenomic next-generation sequencing in the identification of pathogens in pneumonia after congenital heart surgery: a comparative diagnostic accuracy study

Ital J Pediatr. 2024 Sep 12;50(1):174. doi: 10.1186/s13052-024-01749-z. ABSTRACT BACKGROUND: This study aimed to compare targeted next-generation sequencing (tNGS) with metagenomic next-generation sequencing (mNGS) for …

Patient-reported outcome measures for acute rhinosinusitis in adults and children: a systematic review of the quality of existing instruments

Health Qual Life Outcomes. 2024 Sep 12;22(1):79. doi: 10.1186/s12955-024-02289-0. ABSTRACT BACKGROUND: Acute rhinosinusitis (ARS) is a self-limiting inflammation of the nose and sinuses caused by …

Single-cell sequencing of the vermiform appendix during development identifies transcriptional relationships with appendicitis in preschool children

BMC Med. 2024 Sep 12;22(1):383. doi: 10.1186/s12916-024-03611-9. ABSTRACT BACKGROUND: The development of the human vermiform appendix at the cellular level, as well as its function, …