paediatrics
paediatrics

Transcriptomic Landscape Analysis Reveals a Persistent DNA Damage Response in Metabolic Dysfunction-associated Steatohepatitis Post-dietary Intervention

J Clin Transl Hepatol. 2024 Sep 28;12(9):765-779. doi: 10.14218/JCTH.2024.00111. Epub 2024 Aug 2. ABSTRACT BACKGROUND AND AIMS: Metabolic dysfunction-associated steatotic liver disease (MASLD) and its …

Nutrigenomic underpinnings of intestinal stem cells in inflammatory bowel disease and colorectal cancer development

Front Genet. 2024 Aug 30;15:1349717. doi: 10.3389/fgene.2024.1349717. eCollection 2024. ABSTRACT Food-gene interaction has been identified as a leading risk factor for inflammatory bowel disease (IBD) …

Large-scale exome array summary statistics resources for glycemic traits to aid effector gene prioritization

Wellcome Open Res. 2023 Oct 20;8:483. doi: 10.12688/wellcomeopenres.18754.1. eCollection 2023. ABSTRACT BACKGROUND: Genome-wide association studies for glycemic traits have identified hundreds of loci associated with …

Efficacy and safety of tocilizumab in Chinese patients with systemic juvenile idiopathic arthritis: a multicentre phase IV trial

Clin Rheumatol. 2024 Sep 16. doi: 10.1007/s10067-024-07126-9. Online ahead of print. ABSTRACT OBJECTIVES: Given the limited tocilizumab (TCZ) treatment data for systemic juvenile idiopathic arthritis …

Investigation of the effectiveness of preoperative intubation simulation using a custom-made simulator for pediatric patients with difficult airway: a pilot study

J Anesth. 2024 Sep 15. doi: 10.1007/s00540-024-03407-4. Online ahead of print. ABSTRACT The purpose of this study is to investigate whether preoperative intubation simulation using …

Etiology, clinical profile, and outcomes of crescentic glomerulonephritis in children: a systematic review

Pediatr Nephrol. 2024 Sep 16. doi: 10.1007/s00467-024-06521-3. Online ahead of print. ABSTRACT BACKGROUND: Crescentic glomerulonephritis, if not managed promptly, is associated with unsatisfactory outcomes. There …