paediatrics
paediatrics

Understanding Voriconazole Metabolism: A Middle-Out Physiologically-Based Pharmacokinetic Modelling Framework Integrating In Vitro and Clinical Insights

Clin Pharmacokinet. 2024 Oct 30. doi: 10.1007/s40262-024-01434-8. Online ahead of print. ABSTRACT BACKGROUND AND OBJECTIVE: Voriconazole (VRC), a broad-spectrum antifungal drug, exhibits nonlinear pharmacokinetics (PK) …

Normal values and distribution of ventricular global longitudinal strain in 513 healthy fetuses measured by two-dimensional speckle-tracking echocardiography: a multi-institutional cohort study

Heart Vessels. 2024 Oct 30. doi: 10.1007/s00380-024-02477-4. Online ahead of print. ABSTRACT This study aimed to determine the normal reference values and distribution of global …

Cardiovascular magnetic resonance semi-automated threshold-based post-processing of right ventricular volumes in repaired tetralogy of Fallot

Radiol Med. 2024 Oct 30. doi: 10.1007/s11547-024-01908-6. Online ahead of print. ABSTRACT BACKGROUND: Cardiovascular magnetic resonance (CMR) is the gold-standard to estimate right ventricular (RV) …

Urgent need for enhanced food safety protocols in fast-food supply chains: lessons from the recent multi-state E. coli outbreak

Infect Dis (Lond). 2024 Oct 30:1-3. doi: 10.1080/23744235.2024.2422519. Online ahead of print. ABSTRACT Recent events, including a multi-state E. coli outbreak linked to McDonald’s, have …