Aerobic capacity and muscle proteome: Insights from a mouse model
Exp Physiol. 2024 Nov 21. doi: 10.1113/EP092308. Online ahead of print. ABSTRACT We explored the association between aerobic capacity (AC) and the skeletal muscle proteome …
paediatrics
Pooled CRISPR screens with joint single-nucleus chromatin accessibility and transcriptome profiling
Nat Biotechnol. 2024 Nov 21. doi: 10.1038/s41587-024-02475-x. Online ahead of print. ABSTRACT Pooled single-cell CRISPR screens have profiled either gene expression or chromatin accessibility but …
Clonal hematopoiesis in large granular lymphocytic leukemia
Leukemia. 2024 Nov 21. doi: 10.1038/s41375-024-02460-y. Online ahead of print. ABSTRACT Past studies described occasional patients with myeloid neoplasms (MN) and coexistent large granular lymphocytic …
Gut flora influences the hypothalamic-gonadal axis to regulate the pathogenesis of obesity-associated precocious puberty
Sci Rep. 2024 Nov 21;14(1):28844. doi: 10.1038/s41598-024-80140-8. ABSTRACT The prevalence of obesity-associated precocious puberty is gradually increasing, but the relationship between gut flora and obesity-associated …
Adding eltrombopag to intensive immunosuppressive therapy for severe aplastic anaemia may help adult patients achieve outcomes similar to paediatric patients
Leukemia. 2024 Nov 21. doi: 10.1038/s41375-024-02450-0. Online ahead of print. NO ABSTRACT PMID:39572710 | DOI:10.1038/s41375-024-02450-0
Post-procedure pain in preterm neonates undergoing retinopathy of prematurity (ROP) screening: a prospective cohort study
J Perinatol. 2024 Nov 21. doi: 10.1038/s41372-024-02107-x. Online ahead of print. ABSTRACT OBJECTIVE: To evaluate the pain intensity in preterm infants during 48 h post …
Phenotype driven molecular genetic test recommendation for diagnosing pediatric rare disorders
NPJ Digit Med. 2024 Nov 21;7(1):333. doi: 10.1038/s41746-024-01331-1. ABSTRACT Patients with rare diseases often experience prolonged diagnostic delays. Ordering appropriate genetic tests is crucial yet …
Doses from ionizing radiation in pediatric cardiac catheterizations in Norway 1975- 2021
J Radiol Prot. 2024 Nov 21. doi: 10.1088/1361-6498/ad958e. Online ahead of print. ABSTRACT Pediatric patients with congenital heart disease often undergo cardiac catheterization procedures and …
Reirradiation in Paediatric Tumours of the Central Nervous System: Outcome and Side Effects After Implementing National Guidelines
Clin Oncol (R Coll Radiol). 2024 Oct 28;37:103667. doi: 10.1016/j.clon.2024.103667. Online ahead of print. ABSTRACT AIMS: Reirradiation is becoming more frequently used in paediatric tumours …
The IsletTester mouse: an immunodeficient model with stable hyperglycemia for the study of human islets
Diabetes. 2024 Nov 21:db230887. doi: 10.2337/db23-0887. Online ahead of print. ABSTRACT The gold standard for assessing the function of human islets or β-like cells derived …