paediatrics
paediatrics

Precision Medicine for High-Risk Gene Fusions in Pediatric AML: a focus on KMT2A, NUP98, and GLIS2 Rearrangements

Blood. 2025 Jan 14:blood.2024026598. doi: 10.1182/blood.2024026598. Online ahead of print. ABSTRACT Robust genetic characterization of paediatric AML has demonstrated that fusion oncogenes are highly prevalent …

Subclonal TP53 and KRAS variants combined with poor treatment response identify ultra-high-risk pediatric T-ALL patients

Blood Adv. 2025 Jan 14:bloodadvances.2024014209. doi: 10.1182/bloodadvances.2024014209. Online ahead of print. ABSTRACT Variations in the TP53 and KRAS genes indicate a particularly adverse prognosis in …

Precision Medicine Proof-of-Concept Study of a TNF Inhibitor in FSGS and Treatment-Resistant Minimal Change Disease

Kidney360. 2024 Nov 18. doi: 10.34067/KID.0000000635. Online ahead of print. ABSTRACT BACKGROUND: Focal segmental glomerulosclerosis (FSGS) and treatment-resistant minimal change disease (TR-MCD) are heterogeneous disorders …

Transcatheter edge-to-edge repair of severe atrioventricular valve regurgitation in unrepaired functionally univentricular heart with dextroversion

J Invasive Cardiol. 2025 Jan 13. doi: 10.25270/jic/24.00359. Online ahead of print. NO ABSTRACT PMID:39808458 | DOI:10.25270/jic/24.00359