paediatrics
paediatrics

TLR ligand sensing by lymph node FRCs directs intranodal lymphocyte accumulation to promote immune responses

iScience. 2025 Oct 8;28(11):113734. doi: 10.1016/j.isci.2025.113734. eCollection 2025 Nov 21. ABSTRACT Immune protection depends on antigen-responsive lymphocytes finding their cognate antigen on competent antigen-presenting cells. …

Corrigendum to “Distribution of virulence genes and antimicrobial resistance of Escherichia coli isolated from hospitalized neonates: A multi-center study across China” [Heliyon Volume 10, Issue 16, August 30, 2024, Article e35991]

Heliyon. 2025 Jun 12;11(12):e43468. doi: 10.1016/j.heliyon.2025.e43468. eCollection 2025 Jul. ABSTRACT [This corrects the article DOI: 10.1016/j.heliyon.2024.e35991.]. PMID:41216568 | PMC:PMC12435056 | DOI:10.1016/j.heliyon.2025.e43468

Developmental outcomes after soybean oil vs mixed-oil intravenous lipid emulsions in neonates: A secondary analysis of a clinical trial

JPEN J Parenter Enteral Nutr. 2025 Nov 10. doi: 10.1002/jpen.70032. Online ahead of print. ABSTRACT BACKGROUND: Fatty acids make up a significant portion of brain …

Chronic hypoxia impairs L-type Ca2+ channel-mediated myogenic vasoconstriction and cerebral autoregulation in newborn lambs

J Physiol. 2025 Nov 10. doi: 10.1113/JP289790. Online ahead of print. ABSTRACT Cerebral autoregulation is a vital homeostatic mechanism that protects the brain from hypertension-induced …

Targeted congenital cytomegalovirus screening as part of the newborn hearing screening programme in Northeast England

Eur J Pediatr. 2025 Nov 11;184(12):747. doi: 10.1007/s00431-025-06612-9. ABSTRACT Neonates with congenital CMV (cCMV) with hearing loss at birth have improved hearing and developmental outcomes …

Development, Verification, and Application of a Chinese Pediatric Physiologically Based Pharmacokinetic Model: Emphasis on CYP Metabolism and Renal Elimination

AAPS J. 2025 Nov 10;28(1):17. doi: 10.1208/s12248-025-01151-5. ABSTRACT Physiologically based pharmacokinetics (PBPK) models are increasingly being used in pediatric drug development and with the conduct …