paediatrics
paediatrics

Modelling a pathological GSX2 variant that selectively alters DNA binding reveals hypomorphic mouse basal ganglia and hindbrain defects

Dis Model Mech. 2025 Jan 30:dmm.052110. doi: 10.1242/dmm.052110. Online ahead of print. ABSTRACT Gsx2 is a homeodomain transcription factor critical for development of the ventral …

Carbapenem-resistant Enterobacterales infection and colonization in patients with severe burns: a retrospective cohort study in a single burn center

Antimicrob Resist Infect Control. 2025 Jan 29;14(1):3. doi: 10.1186/s13756-025-01514-9. ABSTRACT BACKGROUND: Clinical characteristics and outcomes of carbapenem-resistant Enterobacterales (CRE) infection and colonization have rarely been …

Association of systemic immune-inflammation index (SII) with risk of psoriasis: a cross-sectional analysis of National Health and Nutrition Examination Survey 2011-2014

Eur J Med Res. 2025 Jan 29;30(1):58. doi: 10.1186/s40001-025-02304-0. ABSTRACT BACKGROUND: The systemic immune-inflammation index (SII) is an emerging marker of inflammation, and the onset …

Simulation-based training program effect on pediatric nurses’ knowledge and performance regarding heel-prick during newborn blood screening test

BMC Nurs. 2025 Jan 29;24(1):110. doi: 10.1186/s12912-024-02657-7. ABSTRACT BACKGROUND: One of the best ways to impart important skills to trainees is through simulation-based training, which …

Alpha/beta values in pediatric medulloblastoma: implications for tailored approaches in radiation oncology

Radiat Oncol. 2025 Jan 29;20(1):17. doi: 10.1186/s13014-024-02566-8. ABSTRACT BACKGROUND: Medulloblastoma is the most common malignant pediatric brain tumor, typically treated with normofractionated craniospinal irradiation (CSI) …

Comparison of clinical and virological features in pediatric and adult dengue cases at Insein General Hospital during Myanmar’s 2022 dengue season

Trop Med Health. 2025 Jan 29;53(1):13. doi: 10.1186/s41182-025-00688-7. ABSTRACT BACKGROUND: Myanmar is one of the countries in Southeast Asia where serious dengue outbreaks occur and …

Metabolic/bariatric surgery optimization: a position statement by Arabic association for the study of diabetes and metabolism (AASD)

Diabetol Metab Syndr. 2025 Jan 29;17(1):37. doi: 10.1186/s13098-024-01564-w. ABSTRACT For patients considering bariatric surgery, it is essential to have clear answers to common questions to …

Spectrophotometric and computational characterization of charge transfer complex of selumetinib with 2,3-dichloro-5,6-dicyano-1,4-benzoquinone and its utilization in developing an innovative green and high throughput microwell assay for analysis of bulk form and pharmaceutical formulation

BMC Chem. 2025 Jan 29;19(1):27. doi: 10.1186/s13065-024-01353-6. ABSTRACT For paediatric patients suffering from neurofibromatosis, Selumetinib (SEL) is the only approved drug. Here an original ecofriendly …

Understanding the local-level variations in seasonality of human respiratory syncytial virus infection: a systematic analysis

BMC Med. 2025 Jan 29;23(1):55. doi: 10.1186/s12916-025-03888-4. ABSTRACT BACKGROUND: While previous reports characterised global and regional variations in RSV seasonality, less is known about local …

Risk of stroke associated with proton pump inhibitor use among individuals with and without pre-existing cardiovascular diseases: a systematic review and meta-analysis

J Cardiothorac Surg. 2025 Jan 29;20(1):107. doi: 10.1186/s13019-024-03161-4. ABSTRACT BACKGROUND: Proton pump inhibitors (PPIs) are commonly used for managing gastroesophageal disorders but concerns about their …