Negative Control Outcome Adjustment in Early-Phase Randomized Trials: Estimating Vaccine Effects on Immune Responses in HIV Exposed Uninfected Infants
Stat Med. 2025 Jun;44(13-14):e70142. doi: 10.1002/sim.70142. ABSTRACT Adjustment for prognostic baseline variables can reduce bias due to covariate imbalance and increase efficiency in randomized trials. …