neonatal
neonatal

Pancreatic, nutritional and clinical outcomes in children 0-5 years with cystic fibrosis during the first 2 years of CFTR modulator therapy (PaNC): a multicentre prospective observational study protocol

BMJ Open. 2025 Jul 30;15(7):e097071. doi: 10.1136/bmjopen-2024-097071. ABSTRACT BACKGROUND: Cystic fibrosis (CF) is a genetic condition of impaired membrane electrolyte transport and is characterised by …

Development of a machine learning-based prediction model for serious bacterial infections in febrile young infants

BMJ Paediatr Open. 2025 Jul 30;9(1):e003548. doi: 10.1136/bmjpo-2025-003548. ABSTRACT BACKGROUND: To develop and validate machine learning (ML)-based models to predict serious bacterial infections (SBIs) in …

Maternal diet shapes infant microbiota and defensive capacity against infections in early life via differential human milk composition

EBioMedicine. 2025 Jul 29;118:105850. doi: 10.1016/j.ebiom.2025.105850. Online ahead of print. ABSTRACT BACKGROUND: Maternal nutritional status and dietary profile during pregnancy and lactation have short- and …

Impairment of stromal-epithelial regenerative cross-talk in Hirschsprung disease primes for the progression to enterocolitis

Sci Transl Med. 2025 Jul 30;17(809):eadp4679. doi: 10.1126/scitranslmed.adp4679. Epub 2025 Jul 30. ABSTRACT Hirschsprung disease (HSCR) is a congenital condition characterized by the improper migration …

Lineage trajectories and fate determinants of postnatal neural stem cells and ependymal cells in the developing ventricular zone

PLoS Biol. 2025 Jul 30;23(7):e3003318. doi: 10.1371/journal.pbio.3003318. Online ahead of print. ABSTRACT The ventricular zone (VZ) harbors the largest neurogenic niche in the adult mammalian …