neonatal
neonatal

Clinical outcomes after implementation of a physiologic pre-operative management strategy in neonates with congenital diaphragmatic hernia

J Perinatol. 2025 Jul 18. doi: 10.1038/s41372-025-02362-6. Online ahead of print. ABSTRACT OBJECTIVE: To evaluate neonatal outcomes in congenital diaphragmatic hernia (CDH) after implementation of …

Cellular crosstalk mediated by TGF-β drives epithelial-mesenchymal transition in patient-derived multi-compartment biliary organoids

Nat Commun. 2025 Jul 17;16(1):6575. doi: 10.1038/s41467-025-61442-5. ABSTRACT Deficiencies in the development of epithelial structures and delays in cellular maturation can increase the susceptibility of …

Integrating the Continuum of Genetic Testing From Fetus to Neonate: A Review of Prenatal Genetic Testing and the Overlap With Newborn Testing

Prenat Diagn. 2025 Jul 17. doi: 10.1002/pd.6849. Online ahead of print. ABSTRACT Perinatal genetics is a field that continues to experience rapid advances. Various genetic …

Novel GLP-1/GIP Dual Receptor Agonist Alleviates Neonatal Hypoxic-Ischemic Encephalopathy by Inhibiting TLR2/NF-kappaB/NLRP3 Mediated-Neuroinflammation : The role of DA5-CH in neonatal hypoxic-ischemic encephalopathy

Neurochem Res. 2025 Jul 17;50(4):235. doi: 10.1007/s11064-025-04475-y. ABSTRACT Hypoxic-ischemic encephalopathy (HIE) is an irreversible brain injury attributable to impaired blood oxygen delivery in the brain …

Externally validated population pharmacokinetics of amikacin and evaluation of dosage regimen based on achieved serum concentrations in neonates

Antimicrob Agents Chemother. 2025 Jul 17:e0081825. doi: 10.1128/aac.00818-25. Online ahead of print. ABSTRACT Combination antibiotics consisting of beta-lactam and aminoglycoside are commonly utilized in the …

Survival to Hospital Discharge in the Fetus With Moderate to Severe Mitral Regurgitation Either in Isolation or in Combination With Aortic Valve Stenosis or Atresia, a Fetal Heart Society Collaborative Study

J Am Heart Assoc. 2025 Jul 17:e041677. doi: 10.1161/JAHA.125.041677. Online ahead of print. ABSTRACT BACKGROUND: Case series report high mortality after fetal diagnosis of moderate …