neonatal
neonatal

Fazirsiran for the treatment of alpha-1 antitrypsin deficiency-associated liver disease findings from the SEQUOIA phase 2 trial

Ann Med Surg (Lond). 2025 May 30;87(7):4014-4016. doi: 10.1097/MS9.0000000000003393. eCollection 2025 Jul. ABSTRACT Alpha-1 antitrypsin deficiency (AATD) is a prevalent autosomal recessive disorder affecting approximately …

Angiotensin II-induced phosphorylation of CHK1 at serine-280 drives cardiac remodelling by direct phosphorylation of JAK1, thus activating JAK1-STAT signalling in murine cardiomyocytes

Br J Pharmacol. 2025 Aug 24. doi: 10.1111/bph.70180. Online ahead of print. ABSTRACT BACKGROUND AND PURPOSE: Cardiac remodelling is a common pathological process of heart …

Comparing spinal anaesthesia and epidural anaesthesia in cephalic external version: a protocol for systematic review and network meta-analysis

BMJ Open. 2025 Aug 24;15(8):e087603. doi: 10.1136/bmjopen-2024-087603. ABSTRACT INTRODUCTION: Breech presentation, occurring in approximately 3-5% of term pregnancies, is associated with increased risks of complications …