medicine
medicine

Intestinal metabolomics analysis reveals lysophosphatidylcholine is the key regulatory metabolite in mouse models of necrotizing enterocolitis

Sci Rep. 2025 Oct 23;15(1):37121. doi: 10.1038/s41598-025-21152-w. ABSTRACT Necrotizing enterocolitis (NEC) is a severe intestinal emergency in neonates. This study explored NEC-related biomarkers by metabolomics …

A US case-control study to estimate infant group B streptococcal disease serological thresholds of risk-reduction

Nat Commun. 2025 Oct 23;16(1):9381. doi: 10.1038/s41467-025-64324-y. ABSTRACT Maternal vaccines to prevent infant Group B Streptococcus (GBS) disease have progressed through phase II development and …

Ambient biothermal stress, preconceptional thyrotropin abnormalities, and the risk of preterm birth: a nationwide Chinese cohort study

Nat Commun. 2025 Oct 23;16(1):9372. doi: 10.1038/s41467-025-64410-1. ABSTRACT Epidemiologic evidence on thermal stress and preterm birth (PTB) is based on ambient temperature rather than a …

Clinical characteristics and carbapenem resistance gene of Klebsiella pneumonia isolates from children in Chongqing region from 2019 to 2024

Zhonghua Yu Fang Yi Xue Za Zhi. 2025 Oct 6;59(10):1655-1664. doi: 10.3760/cma.j.cn112150-20250529-00497. ABSTRACT Objective: To investigate the clinical distribution characteristics changes in antimicrobial resistance, and …

Challenges in postoperative management of a patient with primary ciliary dyskinesia and Joubert syndrome and related disorders with congenital heart disease

BMJ Case Rep. 2025 Oct 23;18(10):e267389. doi: 10.1136/bcr-2025-267389. ABSTRACT We report the case of a male infant born at 37 weeks and 4 days of …

Prenatal Insecticide Exposure and Adverse Birth Outcomes: Evidence for Mediation via Disruptions in Amino Acid and Acylcarnitine Metabolism

Environ Sci Technol. 2025 Oct 23. doi: 10.1021/acs.est.5c13454. Online ahead of print. ABSTRACT Maternal exposure to organophosphate (OP) and pyrethroid insecticides may adversely affect newborn …

Stillbirths in Bahrain: Analysis of patients admitted to a major tertiary hospital during a five-year period

J Neonatal Perinatal Med. 2025 Oct 23:19345798251391442. doi: 10.1177/19345798251391442. Online ahead of print. ABSTRACT BackgroundAnalyzing stillbirth data is critical to identifying care gaps and improving …

Clinical Application of Combined Measurement of Cardiac Injury Markers and Platelet Parameters in Pregnant Women with Preeclampsia

Kardiologiia. 2025 Oct 23;65(9):72-81. doi: 10.18087/cardio.2025.9.n2953. ABSTRACT Background Preeclampsia (PE) is a severe pregnancy complication characterized by hypertension and organ damage. Recent evidence suggests that …