medicine
medicine

Genetic Diagnosis in Neonatal Encephalopathy With Hypoxic Brain Damage Using Targeted Gene Panel Sequencing

J Clin Neurol. 2024 Sep;20(5):519-528. doi: 10.3988/jcn.2023.0500. ABSTRACT BACKGROUND AND PURPOSE: Neonatal encephalopathy (NE) is a neurological syndrome that presents with severe neurological impairments and …

Subcutaneous efgartigimod PH20 in generalized myasthenia gravis: A phase 3 randomized noninferiority study (ADAPT-SC) and interim analyses of a long-term open-label extension study (ADAPT-SC+)

Neurotherapeutics. 2024 Sep 2:e00378. doi: 10.1016/j.neurot.2024.e00378. Online ahead of print. ABSTRACT ADAPT-SC (NCT04735432) was designed to evaluate noninferiority of subcutaneous (SC) efgartigimod PH20 to intravenous …

Tanomastat exerts multi-targeted inhibitory effects on viral capsid dissociation and RNA replication in human enteroviruses

EBioMedicine. 2024 Sep 2;107:105277. doi: 10.1016/j.ebiom.2024.105277. Online ahead of print. ABSTRACT BACKGROUND: Global cyclical outbreaks of human enterovirus infections has positioned human enterovirus A71 (EV-A71) …

Determinants of dropout from the maternal continuum of care in Ethiopia, multilevel analysis of the 2016 demographic and health survey

PLOS Glob Public Health. 2024 Sep 3;4(9):e0003641. doi: 10.1371/journal.pgph.0003641. eCollection 2024. ABSTRACT Over the past two decades (2000-2020), Ethiopia achieved significant reductions in maternal and …

Prenatal Exposure to Per- and Polyfluoroalkyl Substances and ASD-Related Symptoms in Early Childhood: Mediation Role of Steroids

Environ Sci Technol. 2024 Sep 3. doi: 10.1021/acs.est.4c04500. Online ahead of print. ABSTRACT Previous studies regarding the associations between perfluoroalkyl and polyfluoroalkyl substances (PFAS) and …

Are important predictors of adverse outcome in children with symptomatic congenital cytomegalovirus infection overlooked in clinical settings?

J Int Med Res. 2024 Sep;52(9):3000605241274226. doi: 10.1177/03000605241274226. ABSTRACT OBJECTIVE: Congenital cytomegalovirus infection (cCMV) is a common, frequently unrecognized cause of childhood disability. The aim …