medicine
medicine

Continuous wireless sensor monitoring with applied diagnostics: Clinical Sensor Pain Scale and Automated Sensor Pain Scale in the NICU

BMJ Health Care Inform. 2025 Nov 21;32(1):e101283. doi: 10.1136/bmjhci-2024-101283. ABSTRACT OBJECTIVES: Inappropriately treated pain can have deleterious outcomes in infants. Current tools rely on intermittent, …

Early language delay among infants with hypoxic-ischaemic encephalopathy after therapeutic hypothermia: A prospective cohort study

Early Hum Dev. 2025 Nov 19;213:106444. doi: 10.1016/j.earlhumdev.2025.106444. Online ahead of print. ABSTRACT AIM: To assess early language development in infants with hypoxic-ischaemic encephalopathy (HIE), …

Photostability of Topoisomerase I Inhibitor Conjugated IgG1 Antibody-Drug Conjugates: Characterization Study and Degradation Mechanism Analysis

Bioconjug Chem. 2025 Nov 22. doi: 10.1021/acs.bioconjchem.5c00485. Online ahead of print. ABSTRACT DNA topoisomerase I (TOP1) inhibitor-based antibody-drug conjugates (ADCs) incorporating photosensitive camptothecin (CPT) analogs …

The cytotoxicity of gomesin peptides is mediated by the glycosphingolipid pathway and lipid-cholesterol interactions

Cell Death Discov. 2025 Nov 21;11(1):538. doi: 10.1038/s41420-025-02817-x. ABSTRACT Gomesins (AgGom and HiGom) are therapeutically promising spider-derived peptides that target a specific phospholipid composition (3PC:1PS:1Chol) …

Perinatal equipment, medication and specialized formula shortages: Defining the challenge and exploring ethical solutions

Semin Perinatol. 2025 Nov 21:152187. doi: 10.1016/j.semperi.2025.152187. Online ahead of print. ABSTRACT Medication, equipment, and formula shortages have become commonplace in the neonatal intensive care …