medicine
medicine

Testing Higher Doses of Sildenafil to Repair Brain Injury Secondary to Birth Asphyxia: An Open-Label Dose-Finding Phase 1b Clinical Trial (SANE-02)

J Pediatr. 2025 Jun 23:114701. doi: 10.1016/j.jpeds.2025.114701. Online ahead of print. ABSTRACT OBJECTIVE: To evaluate the safety and tolerability of higher doses of sildenafil in …

The m5C reader Alyref regulates cardiac remodeling post-myocardial infarction by modulating extracellular matrix protein synthesis in cardiac fibroblasts

Biochim Biophys Acta Mol Cell Res. 2025 Jun 23:120011. doi: 10.1016/j.bbamcr.2025.120011. Online ahead of print. ABSTRACT Myocardial infarction (MI) triggers a significant injury response that …

REVISITING INHALED NITRIC OXIDE UTILIZATION IN CONGENITAL DIAPHRAGMATIC HERNIA: A NATIONAL COHORT STUDY OF MAJOR CHILDREN’S HOSPITALS IN THE UNITED STATES

J Pediatr Surg. 2025 Jun 23:162423. doi: 10.1016/j.jpedsurg.2025.162423. Online ahead of print. ABSTRACT PURPOSE: For over a decade, there has been evidence suggesting a lack …

Excess mortality in winter in Argentina from 1997 to 2017: an approach based on public health and an epistemic dispute from the Global South

Cad Saude Publica. 2025 Jun 20;41(5):e00168524. doi: 10.1590/0102-311XES168524. eCollection 2025. ABSTRACT Excess mortality in winter is studied in the Global North as a manifestation of …

Small and sick newborn care: Changes in service readiness scoring between baseline and 2023 for 65 neonatal units implementing with NEST360 in Kenya, Malawi, Nigeria, and Tanzania

PLOS Glob Public Health. 2025 Jun 25;5(6):e0004367. doi: 10.1371/journal.pgph.0004367. eCollection 2025. ABSTRACT Health Facility Assessments (HFAs) are important for measuring and tracking service readiness for …

Cost-effectiveness of immunization strategies to protect infants against respiratory syncytial virus in the Netherlands

Hum Vaccin Immunother. 2025 Dec;21(1):2521912. doi: 10.1080/21645515.2025.2521912. Epub 2025 Jun 25. ABSTRACT The European Medicines Agency has authorized two interventions to prevent lower respiratory tract …

Effects of maternal anemia on low-birth-weight in Sub-Sahara African countries: Systematic review and meta-analysis

PLoS One. 2025 Jun 25;20(6):e0325450. doi: 10.1371/journal.pone.0325450. eCollection 2025. ABSTRACT INTRODUCTION: Maternal anemia is a major public health concern that affects women globally, with a …

Protocol: the International Milk Composition (IMiC) Consortium – a harmonized secondary analysis of human milk from four studies

Front Nutr. 2025 Jun 10;12:1548739. doi: 10.3389/fnut.2025.1548739. eCollection 2025. ABSTRACT INTRODUCTION: Human milk (HM) contains a multitude of nutritive and nonnutritive bioactive compounds that support …