medicine
medicine

Machine Learning Resolves Functional Phenotypes and Therapeutic Responses in KCNQ2 Developmental Epileptic Encephalopathy iPSC Models

bioRxiv [Preprint]. 2025 Jul 31:2025.07.26.666977. doi: 10.1101/2025.07.26.666977. ABSTRACT Pathogenic KCNQ2 variants are associated with developmental and epileptic encephalopathy (KCNQ2-DEE), a devastating disorder characterized by neonatal-onset …

Factors influencing the implementation of Integrated Management of Neonatal and Childhood Illness (IMNCI) by nurses in Bhutan: A predictive correlational study

Belitung Nurs J. 2025 Aug 3;11(4):478-486. doi: 10.33546/bnj.3816. eCollection 2025. ABSTRACT BACKGROUND: Integrated Management of Neonatal and Childhood Illness (IMNCI) is a critical strategy aimed …

Comparison of hyperbaric bupivacaine with fentanyl vs. hyperbaric bupivacaine with dexmedetomidine in reducing visceral pain during cesarean delivery under spinal anesthesia: study protocol

Pain Manag. 2025 Aug 6:1-8. doi: 10.1080/17581869.2025.2543232. Online ahead of print. ABSTRACT BACKGROUND: The primary objective of this randomized, double-blind, parallel-group trial is to evaluate …

Comparative analysis of bevacizumab and sorafenib on the survival of retinal ganglion cells in the treatment of retinal diseases

Sci Rep. 2025 Aug 5;15(1):28587. doi: 10.1038/s41598-025-12199-w. ABSTRACT This study investigates the effects of bevacizumab, a common vascular endothelial growth factor (VEGF) inhibitor, in treating …