medicine
medicine

Assessing solubility of meloxicam in age-specific gastric and intestinal media relevant to adults and pediatric populations: implications for optimizing dosing in patients for postoperative pain

BMC Pharmacol Toxicol. 2024 Oct 9;25(1):75. doi: 10.1186/s40360-024-00799-7. ABSTRACT BACKGROUND: Oral dose formulations must be soluble in gastrointestinal fluids for systemic absorption. The solubility of …

Factors influencing the acceptability of the test, treat and refer practice for malaria among caregivers of under 5 children at community pharmacies and drug shops in Nigeria

Malar J. 2024 Oct 9;23(1):304. doi: 10.1186/s12936-024-05114-7. ABSTRACT BACKGROUND: Malaria affects children under the age of five and pregnant women, leading to high morbidity and …

Novel Compound Heterozygous Variants in the FAS Gene Lead to Fetal Onset of Autoimmune Lymphoproliferative Syndrome (ALPS)

J Clin Immunol. 2024 Oct 10;45(1):23. doi: 10.1007/s10875-024-01812-8. ABSTRACT OBJECTIVE: FAS gene defects lead to autoimmune lymphoproliferative syndrome (ALPS), which is often inherited in an …

Mediastinal Shift Index: A Novel Postnatal Measurement of Mediastinal Movement that Predicts Survival in Neonates With Congenital Diaphragmatic Hernia on Extracorporeal Membrane Oxygenation

J Pediatr Surg. 2024 Sep 14:161922. doi: 10.1016/j.jpedsurg.2024.161922. Online ahead of print. ABSTRACT PURPOSE: Mediastinal position varies in neonates with congenital diaphragmatic hernia (CDH), reflecting …