Shared metabolic and stress pathways to neonatal adiposity
Shared metabolic and stress pathways to neonatal adiposity

Shared metabolic and stress pathways to neonatal adiposity

Trends Endocrinol Metab. 2024 Dec 18:S1043-2760(24)00319-9. doi: 10.1016/j.tem.2024.11.012. Online ahead of print.

ABSTRACT

Perceived stress levels, prevalence of pregnancies complicated by metabolic disorders, and childhood obesity have been increasing steadily. We here propose a pathway integrating stress-responsive biological systems into the established effects of maternal diabetes and obesity during pregnancy, overall exerting a combined contribution to offspring adiposity risk.

PMID:39701916 | DOI:10.1016/j.tem.2024.11.012