BMC Endocr Disord. 2024 Aug 30;24(1):166. doi: 10.1186/s12902-024-01700-7.
ABSTRACT
OBJECTIVE: This Study aims to investigate the risk factors of hypoglycemia in neonates through meta-analysis.
METHOD: PubMed, Embase, Cochrane library, and Web of science databases were searched for case-control studies on risk factors for neonatal hypoglycemia. The search was done up to 1st October 2023 and Stata 15.0 was used for data analysis.
RESULTS: A total of 12 published studies were included, including 991 neonates in the hypoglycemic group and 4388 neonates in the non-hypoglycemic group. Meta-analysis results suggested caesarean section [OR = 1.90 95%CI (1.23, 2.92)], small gestational age[OR = 2.88, 95%CI (1.59, 5.20)], gestational diabetes [OR = 1.65, 95%CI (1.11, 2.46)], gestational hypertension[OR = 2,79, 95%CI (1.78, 4.35)] and respiratory distress syndrome[OR = 5.33, 95%CI (2.22, 12.84)] were risk factors for neonatal hypoglycemia.
CONCLUSION: Based on the current study, we found that caesarean section, small gestational age, gestational diabetes, gestational hypertension, respiratory distress syndrome are risk factors for neonatal hypoglycemia.
PROSPERO REGISTRATION NUMBER: CRD42023472974.
PMID:39215269 | DOI:10.1186/s12902-024-01700-7
