Relationship Between Urine Serotonin and Persistent Pulmonary Hypertension of the Newborn
Relationship Between Urine Serotonin and Persistent Pulmonary Hypertension of the Newborn

Relationship Between Urine Serotonin and Persistent Pulmonary Hypertension of the Newborn

J Pediatr. 2024 Sep 4:114290. doi: 10.1016/j.jpeds.2024.114290. Online ahead of print.

ABSTRACT

Urine serotonin (5-HT)/creatinine was lower at day of life 3 in newborns with pulmonary hypertension compared with controls, while the percent change in the 5-HT metabolite, 5-hydroxyindoleacetic acid (5-HIAA)/creatinine increased. We speculate that the changes in 5-HT and 5-HIAA reflect enhanced pulmonary 5-HT uptake and/or metabolism.

PMID:39242076 | DOI:10.1016/j.jpeds.2024.114290