Oncocytic Adrenocortical Carcinoma in an Infant: Clinical Findings and Imaging Features
Oncocytic Adrenocortical Carcinoma in an Infant: Clinical Findings and Imaging Features

Oncocytic Adrenocortical Carcinoma in an Infant: Clinical Findings and Imaging Features

Clin Nucl Med. 2025 Nov 7. doi: 10.1097/RLU.0000000000006208. Online ahead of print.

ABSTRACT

Pediatric adrenocortical carcinoma (ACC) is rare malignancy, and its oncocytic variant is exceptionally rare in infants. A 1-year-old girl presented with excessive hair growth and hoarseness of voice for 8 months of age. Investigations revealed elevated androgen levels, and whole-body 18F FDG PET-CT imaging showed an isolated large left adrenal mass. The mass was surgically excised, and histopathology confirmed oncocytic adrenocortical carcinoma with a Wieneke score of 5, indicating malignancy. The postoperative course was uneventful with stabilization on antihypertensive and corticosteroid therapy.

PMID:41288997 | DOI:10.1097/RLU.0000000000006208